AngioDynamics NanoKnife Electrostimulation

AngioDynamics NanoKnife – Advanced Irreversible Electroporation System for Precision Tumor Ablation

The AngioDynamics NanoKnife is an innovative soft-tissue ablation system that uses Irreversible Electroporation (IRE) technology to destroy cancerous cells with precision and minimal collateral damage. Unlike heat-based ablation systems, the NanoKnife uses powerful, high-voltage electrical pulses to permanently disrupt cell membranes while preserving critical structures such as blood vessels, ducts, and connective tissue. This makes it an essential tool for treating tumors located near sensitive anatomy.

Developed for use in general surgery, interventional oncology, and minimally invasive procedures, the NanoKnife system offers highly targeted ablation with predictable, uniform results—expanding treatment possibilities for patients with unresectable or difficult-to-reach tumors.

Key Features

• Irreversible Electroporation (IRE) Technology
Utilizes electric pulses to create nanoscale pores in cell membranes, leading to natural cell death without heat-induced damage.
• Non-Thermal Tissue Ablation
Protects vital structures, making it ideal for tumors near nerves, vessels, and bile ducts.
• Precision Electrode Placement
Multiple needle electrodes allow customizable geometry and accurate treatment zones based on tumor size and shape.
• Real-Time Monitoring & Control
Advanced software tracks pulse delivery, impedance, and system performance for safe and reliable procedures.
• Minimally Invasive
Reduced trauma, faster recovery, and improved patient tolerance compared to traditional ablation methods.

Clinical Applications

• Liver tumors (primary and metastatic)
• Pancreatic lesions
• Prostate tumor ablation
• Soft-tissue oncology
• Ablation near critical structures that limit thermal technologies

Benefits

✓ Non-thermal and tissue-sparing
✓ Allows treatment of tumors unsuitable for heat-based ablation
✓ Customized ablation zones for precise control
✓ Minimally invasive with reduced recovery time
✓ High safety profile for delicate anatomical regions

Why Choose the AngioDynamics NanoKnife?

The NanoKnife Electroporation System provides clinicians with a unique, next-generation ablation platform that expands treatment options for challenging tumors. Its non-thermal IRE approach delivers unparalleled precision, making it a powerful solution for modern interventional oncology and advanced surgical care.